The cave of Agia Sophia is 47 km southwest of Crete, in the gorge of Topolia. At the entrance to the cave, there is a church in honor of Saint Sophia. The entrance has an opening of 25 meters, while the height of the cave reaches 20 meters.

The archaeological presence of the cave is of great importance, as elements have been found in,  from the Neolithic, the classical and the romantic period. Additionally, ceramics, from Neolithic, Early Minoan, Late Minoan, Classical, Hellenistic and Greek years, have been found and a clay image of the 4th century BC.

The cave is particularly impressive because of its height and is full of stalagmites.

  In the cave of Saint Sophia, lives the spider Pholcus creticus, a rare species.